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. 2020 Jun 17;15(6):e0233840. doi: 10.1371/journal.pone.0233840

Table 6. Cohorts 1 and 2—Comparison of key parameters of true-immunizations.

Cohort 1 Cohort 2
Number of Subjects 11 10 p
Median Range Median Range
Total all bites 1323 1111–1574 1136 976–1333 0.004
% mosquitoes infected 80 70–87 88 83–93 0.001
Total infected bites 1007 810–1235 1026 839–1131 0.65
Median bites per immun. 210 175–239 220 77–270 0.4
Bites 1st immun. 175 148–264 227 194–249 0.005
Bites 5th immun. 239 186–272 77 41–96 0.0001
Bites 2nd-4th immun. 210 175–210 221 191–3271 0.2
Duration immun. (days) 119 119–119 119 119–119 1
Interval before CHMI (days) 22 22–24 23 22–24 1
Gland score during immun. 3.2 2.7–3.7 3.6 2.9–3.9 0.02
Gland score 1st immun. 3.3 3.1–3.6 3.4 2.9–3.6 0.75
Gland score 5th immun. 3.2 3.0–3.4 3.7 3.5–3.9 0.0001
Gland score 2nd-4th immun. 3.2 2.7–3.7 3.6 3.4–3.9 0.0001
Gland score CHMI 3.6 2.8–3.8 3.5 3.0–3.8 0.65

Summaries (mean, range) of immunizations in Cohorts 1 and 2 were compared using the Mann Whitney U test, where significance is p = ≤0.05.