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. 2020 Jun 3;6(2):e001202. doi: 10.1136/rmdopen-2020-001202

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Seasonality analysis. Rose diagrams of the Rayleigh test showing the number of patients categorised by months of disease onset. The radius of each sector of the circle indicates the number of patients. Inside and outside circles represent 10 and 20 cases, respectively. An arrow indicates the mean direction of the circular data for significant seasonality. (A) Anti-MDA5-positive patients. (B) Anti-ARS-positive patients. Black sectors indicate numbers of patients with anti-Jo-1 antibody. (C) Anti-MDA5-/ARS-negative patients.

ARS, aminoacyl tRNA synthetase; MDA5, melanoma differentiation-associated gene 5.