Table 3.
Child cord blood chemistries and EH tooth locations by maternal treatment group, maternal median 25(OH)D status and by child EH status and extent group
| All (n=161) |
Treatment Group |
Median 25(OH)D Statusc |
||||
|---|---|---|---|---|---|---|
| 400 IU (n=55) |
2000 IU (n=51) |
4000 IU (n=55) |
Deficient or Insufficient (n=58) |
Sufficient or Optimal (n=103) |
||
| Cord Blood Chemistriesa | ||||||
| 25(OH)D (ng/mL) | 22.2 (10.5) | 17.3 (8.9) | 21.7 (9.6) | 27.7 (10.4) | 14.0 (8.6) | 26.8 (8.6) |
| 1,25(OH)2D (pg/mL) | 37.2 (14.9) | 31.4 (9.6) | 39.5 (17.9) | 40.9 (14.3) | 32.9 (13.4) | 39.1 (15.3) |
| iPTH (pg/mL) | 9.8 (9.4) | 10.2 (11.4) | 9.9 (9.3) | 9.3 (6.8) | 12.2 (11.1) | 8.5 (8.1) |
| Calcium (mg/dL) | 10.1 (0.6) | 10.1 (0.6) | 9.9 (0.7) | 10.2 (0.5) | 9.9 (0.7) | 5.9 (0.5) |
| Phosphorus (mg/dL) | 6.0 (1.1) | 6.2 (1.3) | 6.1 (1.0) | 5.8 (1.1) | 6.2 (1.2) | 5.9 (1.1) |
| EH Regionsb | ||||||
| 51 tooth | ||||||
| cervical | 10 (6.2) | 1 (1.8) | 6 (11.8) | 3 (5.5) | 2 (3.4) | 8 (7.8) |
| middle | 14 (8.7) | 1 (1.8) | 6 (11.8) | 7 (12.7) | 6 (10.3) | 8 (7.8) |
| incisal | 29 (18.0) | 10 (18.2) | 11 (21.6) | 8 (14.55) | 11 (19.0) | 18 (17.5) |
| 61 tooth | ||||||
| cervical | 10 (6.2) | 1 (1.8) | 4 (7.8) | 5 (9.09) | 1 (1.7) | 9 (8.7) |
| middle | 15 (9.3) | 1 (1.8) | 6 (11.8) | 8 (14.5) | 4 (6.9) | 11 (10.7) |
| incisal | 29 (18.0) | 12 (21.8) | 6 (11.8) | 11 (20.0) | 11 (19.0) | 18 (17.5) |
| All (n=161) |
Child EH Status |
Child EH Extent Groupd |
||||
|---|---|---|---|---|---|---|
| No EH (n=85) |
EH (n=60) |
No EH (n=85) |
EH=1 (n=23) |
EH>1 (n=32) |
||
| Cord Blood Chemistriesa | ||||||
| 25(OH)D (ng/mL) | 22.2 (10.5) | 22.6 (10.5) | 22.7 (10.4) | 22.6 (10.5) | 23.4 (11.5) | 22.9 (10.2) |
| 1,25(OH)2D (pg/mL) | 37.2 (14.9) | 34.5 (12.8) | 40.6 (15.9) | 34.5 (12.8) | 38.5 (11.6) | 43.1 (18.3) |
| iPTH (pg/mL) | 9.8 (9.4) | 10.5 (9.8) | 6.7 (5.6) | 10.5 (9.8) | 7.1 (6.3) | 6.4 (5.5) |
| Calcium (mg/dL) | 10.1 (0.6) | 10.1 (0.6) | 10.1 (0.7) | 10.1 (0.6) | 10.0 (0.4) | 10.1 (0.8) |
| Phosphorus (mg/dL) | 6.0 (1.1) | 6.1 (1.1) | 5.8 (1.3) | 6.1 (1.1) | 5.9 (1.1) | 5.7 (1.4) |
| EH Regionsb | ||||||
| 51 tooth | ||||||
| cervical | 10 (6.2) | 0 (0.0) | 10 (16.7) | 0 (0.0) | 1 (4.3) | 8 (25.0) |
| middle | 14 (8.7) | 0 (0.0) | 14 (23.3) | 0 (0.0) | 2 (8.7) | 11 (34.4) |
| incisal | 29 (18.0) | 0 (0.0) | 29 (48.3) | 0 (0.0) | 8 (34.8) | 19 (59.4) |
| 61 tooth | ||||||
| cervical | 10 (6.2) | 0 (0.0) | 10 (16.7) | 0 (0.0) | 2 (8.7) | 7 (21.9) |
| middle | 15 (9.3) | 0 (0.0) | 15 (25.0) | 0 (0.0) | 3 (13.0) | 12 (37.5) |
| incisal | 29 (18.0) | 0 (0.0) | 29 (48.3) | 0 (0.0) | 7 (30.4) | 20 (62.5) |
EH, enamel hypoplasia; iPTH, intact parathyroid hormone.
a
For continuous variables, the mean is shown with the standard deviation in parentheses.
b
For categorical variables, the count is displayed with the percent of the corresponding group in parentheses.
c
Median 25(OH)D values for Deficient or Insufficient is < 32 ng/mL and for Sufficient or Optimal is ≥ 32 ng/mL.
d
Child EH Extent Group totals 140 because 5 children had missing data for a region and were not assigned an extent score.