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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Caries Res. 2019 Oct 30;54(1):55–67. doi: 10.1159/000502793

Appendix Table 1.

Week-level values of maternal covariates for calcium homeostasis by maternal treatment group, median 25(OH)D status and child EH and extent

Treatment Group Median 25(OH)D Status Child EH Status Child EH Extent Group
Variable All 400 IU
(n=55)		 2000 IU
(n=51)		 4000 IU
(n=55)		 Deficient/Insufficient
(n=58)		 Sufficient/Optimal
(n=103)		 No EH
(n=85)		 EH
(n=60)		 No EH
(n=85)		 EH=1
(n=23)		 EH>1
(n=32)
25(OH)D
Weeks 12–36 34.5 30.4 34.1 39.0 22.5 41.1 34.1 36.4 34.1 39.5 34.7
(14.7) (13.7) (13.7) (15.3) (9.3) (12.7) (14.7) (14.9) (14.7) (14.9) (14.2)
Week 12 22.3 24.3 20.5 22.0 15.5 26.1 21.8 23.7 21.8 27.8 21.8
(10.2) (12.8) (8.0) (8.9) (6.0) (10.1) (9.7) (113) (9.7) (13.1) (9.4)
Week 16 32.0 31.1 31.5 33.5 21.9 37.7 31.9 34.3 31.9 36.1 33.0
(113) (12.3) (10.1) (113) (8.3) (8.4) (11.2) (111) (11.2) (13.0) (9.7)
Week 20 35.0 32.4 33.2 39.1 23.8 40.9 34.3 37.3 34.3 41.5 35.7
(12.8) (14.0) (10.4) (12.8) (9.2) (10.3) (119) (14.1) (119) (14.0) (13.0)
Week 24 36.6 30.6 36.3 42.7 22.6 44.2 36.5 38.4 36.5 39.7 37.3
(13.9) (13.2) (12.2) (13.7) (8.5) (9.8) (14.7) (12.9) (14.7) (12.0) (13.4)
Week 28 37.5 30.8 38.0 43.7 24.0 44.8 36.6 39.6 36.6 42.6 37.8
(14.3) (12.3) (13.5) (14.4) (8.8) (111) (14.2) (15.0) (14.2) (15.5) (14.5)
Week 32 40.1 33.0 40.2 46.9 25.3 48.6 39.5 41.8 39.5 45.4 39.7
(15.7) (16.0) (14.2) (13.9) (10.8) (11.2) (16.3) (15.5) (16.3) (15.4) (14.4)
Week 36 39.1 31.1 40.0 46.0 24.7 46.9 39.3 41.1 39.3 44.2 38.8
(16.0) (13.6) (16.1) (14.9) (9.8) (13.1) (15.9) (16.3) (15.9) (15.0) (17.0)
1,25(OH)2D
Weeks 12–36 102.0 93.3 105.6 107.3 90.6 108.2 101.0 104.6 101.0 111.1 100.8
(40.5) (33.4) (43.8) (42.3) (32.6) (43.0) (40.1) (41.8) (40.1) (49.3) (35.3)
Week 12 73.2 75.6 73.9 70.2 69.5 75.3 73.2 73.5 73.2 74.3 75.2
(23.6) (24.3) (23.4) (23.3) (22.0) (24.3) (26.8) (20.7) (26.8) (19.9) (21.6)
Week 16 89.7 85.7 87.0 96.5 83.1 93.5 88.3 94.0 88.3 95.1 94.2
(30.3) (28.6) (31.7) (30.0) (31.3) (29.2) (30.9) (31.2) (30.9) (33.9) (30.8)
Week 20 100.8 93.2 100.8 108.4 90.7 106.2 97.8 107.2 97.8 119.4 99.3
(35.3) (31.3) (35.4) (37.9) (30.4) (36.7) (31.8) (39.0) (31.8) (48.0) (29.8)
Week 24 102.5 92.3 108.3 107.2 89.0 110.1 103.2 101.5 103.2 106.0 96.3
(34.9) (31.6) (36.5) (34.9) (28.6) (36.0) (31.8) (39.6) (31.8) (44.8) (34.6)
Week 28 114.6 103.7 120.9 119.5 101.4 121.8 113.7 118.1 113.7 132.6 108.5
(45.5) (40.1) (44.6) (50.4) (36.3) (48.5) (43.2) (48.1) (43.2) (66.5) (30.8)
Week 32 118.0 99.6 127.3 127.7 98.4 129.4 115.5 122.3 115.5 128.0 118.3
(46.4) (32.2) (57.2) (42.6) (28.9) (50.8) (50.4) (43.3) (50.4) (48.6) (39.1)
Week 36 117.4 104.6 124.0 124.1 104.7 124.2 116.4 120.0 116.4 127.2 117.8
(41.7) (35.7) (43.1) (43.9) (36.5) (43.0) (40.5) (44.7) (40.5) (50.5) (41.0)
iPTH
Weeks 12–36 18.5 18.9 18.2 18.3 21.5 16.9 17.8 19.7 17.8 18.7 20.9
(10.5) (10.8) (10.5) (10.3) (10.9) (10.0) (10.7) (10.9) (10.7) (9.0) (12.2)
Week 12 18.8 18.1 18.3 20.0 20.0 18.1 18.8 19.0 18.8 19.7 17.8
(10.6) (10.0) (9.1) (12.3) (9.6) (110) (12.0) (9.3) (12.0) (10.8) (7.9)
Week 16 16.5 15.7 17.5 16.5 18.5 15.4 16.7 16.5 16.7 16.0 17.8
(9.2) (8.2) (111) (8.3) (7.4) (9.9) (10.0) (8.7) (10.0) (8.1) (9.2)
Week 20 16.8 17.0 15.5 17.9 19.2 15.6 15.2 18.7 15.2 19.6 18.4
(9.2) (8.4) (8.8) (10.4) (8.2) (9.5) (8.5) (9.7) (8.5) (10.1) (9.9)
Week 24 18.0 17.9 18.5 17.8 21.2 16.3 17.6 19.4 17.6 17.3 21.6
(10.3) (9.0) (12.3) (9.5) (12.1) (8.8) (9.2) (12.5) (9.2) (8.5) (15.3)
Week 28 20.3 22.0 19.5 19.3 24.7 18.0 19.0 22.4 19.0 20.2 25.3
(11.4) (110) (11.4) (119) (11.2) (10.9) (10.2) (13.7) (10.2) (9.0) (15.9)
Week 32 18.7 20.5 17.5 18.0 22.2 16.7 17.0 21.5 17.0 19.3 23.8
(9.5) (10.7) (8.2) (9.4) (9.6) (8.9) (9.2) (10.1) (9.2) (6.2) (12.1)
Week 36 20.5 21.5 21.3 18.6 25.0 18.0 20.5 20.5 20.5 18.4 22.7
(12.7) (16.0) (11.5) (9.5) (15.2) (10.3) (14.2) (11.5) (14.2) (9.9) (12.7)
Serum Calciuma
Weeks 12–36 9.0 9.0 8.9 9.0 8.9 9.0 9.0 8.9 9.0 8.9 9.0
(0.3) (0.3) (0.4) (0.4) (0.3) (0.4) (0.3) (0.4) (0.3) (0.3) (0.4)
Week 12 9.2 9.2 9.2 9.2 9.2 9.2 9.2 9.2 9.2 9.2 9.2
(0.3) (0.3) (0.3) (0.3) (0.3) (0.3) (0.3) (0.3) (0.3) (0.3) (0.4)
Week 16 9.1 9.1 9.0 9.1 9.1 9.0 9.0 9.1 9.0 9.1 9.1
(0.3) (0.3) (0.3) (0.4) (0.3) (0.3) (0.3) (0.3) (0.3) (0.3) (0.4)
Week 20 9.0 9.0 9.0 9.0 9.0 9.0 9.0 8.9 9.0 8.9 9.0
(0.4) (0.4) (0.4) (0.3) (0.4) (0.3) (0.4) (0.3) (0.4) (0.2) (0.4)
Week 24 8.9 8.9 8.9 9.0 8.8 8.9 8.9 8.9 8.9 8.8 9.0
(0.3) (0.3) (0.4) (0.3) (0.3) (0.3) (0.3) (0.4) (0.3) (0.2) (0.4)
Week 28 8.8 8.8 8.8 8.8 8.8 8.8 8.9 8.8 8.9 8.8 8.8
(0.4) (0.3) (0.3) (0.4) (0.3) (0.4) (0.3) (0.4) (0.3) (0.3) (0.5)
Week 32 8.9 8.9 8.8 9.0 8.8 8.9 8.9 8.8 8.9 8.9 8.8
(0.3) (0.3) (0.3) (0.3) (0.3) (0.3) (0.3) (0.3) (0.3) (0.2) (0.4)
Week 36 8.9 8.9 8.9 9.0 8.8 8.9 8.9 8.9 8.9 8.9 8.9
(0.3) (0.3) (0.3) (0.4) (0.3) (0.4) (0.3) (0.3) (0.3) (0.4) (0.3)
Serum Phosphorus
Weeks 12–36 3.9 3.9 4.0 3.9 3.9 4.0 3.9 3.9 3.9 3.9 3.9
(0.6) (0.6) (0.6) (0.6) (0.6) (0.6) (0.6) (0.5) (0.6) (0.6) (0.5)
Week 12 4.0 4.0 4.0 3.9 3.9 4.0 4.0 4.0 4.0 4.0 4.0
(0.5) (0.5) (0.5) (0.6) (0.5) (0.5) (0.6) (0.5) (0.6) (0.4) (0.5)
Week 16 4.0 4.0 4.1 3.9 4.0 4.0 4.0 4.0 4.0 3.9 4.0
(0.6) (0.6) (0.6) (0.5) (0.6) (0.6) (0.6) (0.6) (0.6) (0.5) (0.6)
Week 20 3.9 4.0 3.9 3.8 3.9 3.9 4.0 3.8 4.0 3.7 3.9
(0.5) (0.5) (0.5) (0.6) (0.5) (0.5) (0.6) (0.5) (0.6) (0.6) (0.5)
Week 24 3.9 3.9 3.8 4.0 3.8 4.0 3.9 3.9 3.9 3.9 3.9
(0.5) (0.5) (0.6) (0.5) (0.5) (0.6) (0.5) (0.6) (0.5) (0.6) (0.5)
Week 28 3.7 3.7 3.9 3.7 3.7 3.8 3.7 3.8 3.7 3.7 3.7
(0.6) (0.5) (0.6) (0.6) (0.6) (0.6) (0.6) (0.6) (0.6) (0.6) (0.5)
Week 32 3.9 3.9 4.0 3.9 3.9 3.9 3.9 3.9 3.9 3.9 3.9
(0.5) (0.6) (0.5) (0.5) (0.5) (0.5) (0.5) (0.5) (0.5) (0.6) (0.5)
Week 36 4.0 4.0 4.1 4.0 3.9 4.1 4.0 4.1 4.0 4.1 4.2
(0.7) (0.7) (0.8) (0.5) (0.7) (0.6) (0.7) (0.5) (0.7) (0.6) (0.52)