Appendix Table 5.
Model selection with continuous maternal median 25(OH)D utilizing truncated Poisson regression to model counts of positive EH scores (EH extent)
Model Selection Stage | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
1 |
2 |
3 |
4 |
5 |
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Model Term | β | exp(β) | β | exp(β) | β | exp(β) | β | exp(β) | β | exp(β) |
Maternal median 25(OH)D | 0.44 | 1.55 | 0.46 | 1.58 | 0.07 | 1.07 | 0.04 | 1.04 | 0.01 | 1.01 |
(−0.42, 1.39) | (0.66, 4.01) | (−0.31, 1.41) | (0.73, 4.10) | (−0.18, 0.33) | (0.84, 1.39) | (−0.20, 0.29) | (0.82, 1.34) | (−0.23, 0.25) | (0.79, 1.28) | |
Child at birth iPTH | −0.08 | 0.92 | −0.05 | 0.95 | −0.05 | 0.95 | −0.05 | 0.95 | −0.06 | 0.94 |
(−0.27, 0.07) | (0.76, 1.07) | (−0.11, 0.00) | (0.90, 1.00) | (−0.11, −0.01) | (0.90, 0.99) | (−0.11, 0.00) | (0.90, 1.00) | (−0.12, −0.01) | (0.89, 0.99) | |
Child at birth 1,25(OH)2D/10 | 0.61 | 1.84 | 0.59 | 1.80 | 0.24 | 1.27 | 0.24 | 1.27 | 0.24 | 1.27 |
(−0.04, 1.35) | (0.96, 3.86) | (−0.08, 1.41) | (0.92, 4.10) | (0.03, 0.44) | (1.03, 1.55) | (0.01, 0.45) | (1.01, 1.57) | (0.01, 0.45) | (1.01, 1.57) | |
Child iPTH*median 25(OH)D | 0.01 | 1.01 | - | - | - | - | - | - | - | - |
(−0.04, 0.06) | (0.96, 1.06) | |||||||||
(Child 1,25(OH)2D/10)*Maternal median 25(OH)D | −0.10 | 0.90 | −0.09 | 0.91 | - | - | - | - | - | - |
(−0.29, 0.07) | (0.75, 1.07) | (−0.31, 0.07) | (0.73, 1.07) | |||||||
Maternal antacid count | −0.12 | 0.89 | −0.12 | 0.89 | −0.12 | 0.89 | −0.12 | 0.89 | - | - |
(−0.28, 0.03) | (0.76, 1.03) | (−0.27, 0.02) | (0.76, 1.02) | (−0.26, 0.02) | (0.77, 1.02) | (−0.27, 0.01) | (0.76, 1.01) | |||
Gestational age/10 | −0.05 | 0.95 | −0.05 | 0.95 | −0.04 | 0.96 | - | - | - | - |
(−0.14, 0.04) | (0.87, 1.04) | (−0.14, 0.03) | (0.87, 1.03) | (−0.12, 0.03) | (0.89, 1.03) | |||||
Maternal age | 0.08 | 1.08 | 0.08 | 1.08 | 0.10 | 1.11 | 0.09 | 1.09 | 0.10 | 1.11 |
(−0.42, 0.59) | (0.66, 1.80) | (−0.40, 0.61) | (0.67, 1.84) | (−0.39, 0.59) | (0.68, 1.80) | (−0.41, 0.60) | (0.66, 1.82) | (−0.38, 0.63) | (0.68, 1.88) | |
Log(maternal BMI) | −0.45 | 0.64 | −0.44 | 0.64 | −0.18 | 0.84 | −0.47 | 0.63 | −0.52 | 0.59 |
(−1.75, 0.61) | (0.17, 1.84) | (−1.65, 0.57) | (0.19, 1.77) | (−1.21, 0.72) | (0.30, 2.05) | (−1.27, 0.20) | (0.28, 1.22) | (−1.32, 0.14) | (0.27, 1.15) | |
Maternal race/ethnicity: white | 0.06 | 1.06 | 0.08 | 1.08 | 0.10 | 1.11 | 0.05 | 1.05 | 0.04 | 1.04 |
(−0.90, 1.45) | (0.41, 4.26) | (−0.82, 1.43) | (0.44, 4.18) | (−0.77, 1.58) | (0.46, 4.85) | (−0.90, 1.12) | (0.41, 3.06) | (−0.78, 1.09) | (0.46, 2.97) | |
Maternal race/ethnicity: black | 0.08 | 1.08 | 0.11 | 1.12 | 0.08 | 1.08 | 0.06 | 1.06 | 0.04 | 1.04 |
(−0.84, 1.53) | (0.43, 4.62) | (−0.70, 1.47) | (0.50, 4.35) | (−0.81, 1.55) | (0.44, 4.71) | (−0.89, 1.15) | (0.41, 3.16) | (−0.74, 1.11) | (0.48, 3.03) | |
Maternal race/ethnicity: Hispanic | 0.03 | 1.03 | 0.06 | 1.06 | 0.06 | 1.06 | 0.02 | 1.02 | 0.04 | 1.04 |
(−0.87, 1.37) | (0.42, 3.94) | (−0.82, 1.42) | (0.44, 4.14) | (−0.85, 1.55) | (0.43, 4.71) | (−0.98, 1.06) | (0.38, 2.89) | (−0.76, 1.13) | (0.47, 3.10) | |
DIC | 307.8 | 308.0 | 309.6 | 309.3 | 310.1 |
The model coefficients (P) from the backwards model selection are displayed along with their 95% credible intervals. Each coefficient and interval is exponentiated to provide the multiplicative effect on the expected counts of EH. A dash (−) indicates that the variable was removed for that stage of selection. The maternal median 25(OH)D represents the continuous dummy variable; iPTH represents the cord blood iPTH concentration (pg/mL), and 1,25/10 represents the child cord blood measurement of 1,25(OH)2D (pg/mL) divided by 10.