Table 2. Summary of GRB7 expression in breast tissue cores.
GRB7 3+ | GRB7 2+ | Grb7 1+ | GRB7 0 | Total | ||||
---|---|---|---|---|---|---|---|---|
c | c/m | c | c/m | c | c/m | c | ||
Normal tissue | 2* | 0 | 1* | 0 | 7* | 0 | 20 | 30 |
Benign (fibroadenoma) | 4* | 0 | 1* | 0 | 3* | 0 | 7 | 15 |
Benign (fibrocystic changes) | 0 | 0 | 0 | 0 | 0 | 0 | 15 | 15 |
Invasive ductal carcinoma | 27 | 42 | 48 | 11 | 94 | 3 | 114 | 339 |
Ductal carcinoma in situ | 5 | 3 | 5 | 0 | 2 | 0 | 13 | 28 |
Invasive lobular carcinoma | 1 | 0 | 1 | 0 | 3 | 0 | 8 | 13 |
Atypical hyperplasia | 2 | 0 | 0 | 0 | 1 | 0 | 2 | 5 |
Mucinous adenocarcinoma | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2 |
Adenoid cystic carcinoma | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Paget’s disease | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
TOTAL | 41 | 45 | 56 | 12 | 110 | 3 | 182 | 449 |
A list of normal and cancerous breast tissues indicating the GRB7 expression levels and frequencies. Under each GRB7 staining intensity (3+, 2+, 1+, 0) are the number of cases that show cytoplasmic staining only (c) or cytoplasmic plus membrane accentuation (c/m). (*) denotes GRB7 expression in the myoepithelial cells.