Table 4. GRB7 cytoplasmic expression and clinico-pathological characteristics in 339 patients with invasive ductal carcinoma of the breast.

			GRB7 expression				Chi-squared p-value
Clinical factor	Categories	0–1 (low)	%	2–3 (high)	%	Total
Age	<50	115	54.76	67	52.34	182	0.6653
	≥50	95	45.24	61	47.66	156
	total	210		128		338
Tumor size	<2 cm	12	5.69	5	3.91	17	0.4664
	≥2 cm	199	94.31	123	96.09	322
	total	211		128		339
Nodes	Neg	148	70.14	88	68.75	236	0.7870
	Pos	63	29.86	40	31.25	103
	total	211		128		339
HER-2	Neg	130	62.20	7	5.47	137	<0.0001
	Equiv	18	8.61	13	10.16	31
	Pos	61	29.19	108	84.38	169
	total	209		128		337
ER	Neg	101	48.56	91	72.22	192	<0.0001
	Pos	107	51.44	35	27.78	142
	total	208		126		334
PR	Neg	114	54.81	103	81.75	217	<0.001
	Pos	94	45.19	23	18.25	117
	total	208		126		334

Descriptive frequency and univariate chi-square p-values for GRB7 protein expression levels in the cytoplasm shown as low (no staining to weak staining, 0 to 1+) vs. high (medium to strong staining, 2+ to 3+). Neg = negative, Pos = positive, Equiv = equivocal. Not all data points were available for all patients.