Example of a predicted WW-domain pentamer structure with all domains misfolded. Domains are colored, and linkers are gray. The order of the colors starting from N-terminus is red, cyan, yellow, green, orange. The black and white beads are the Cβ atoms of Trp (8, 51, 94, 137, 180) and Tyr (20, 63, 109, 152, 195), respectively. An α-helix containing a Trp residue appears in the cyan domain.