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. 2020 Apr 26;24(12):6658–6669. doi: 10.1111/jcmm.15316

Figure 1.

Figure 1

The changes of miR‐145 and autophagy in mice with intimal hyperplasia. The left carotid arteries of male C57BL/6J mice were ligated with silk suture. The right carotid arteries were used as the control. After 28 days, both carotid arteries were harvested. A, B, Representative sections of control and ligated arteries stained with H&E and the quantification data of carotid artery thickness (Scale bar = 50 μm), n = 8. C, The expression of PCNA protein in carotid arteries was detected by Western blotting. D, The expression of miR‐145 in carotid arteries was detected by real‐time PCR. E, F, The conversion of LC3 I to LC3 II and the expression of Beclin1 in carotid arteries were detected by Western blotting. G, The expression of p62 in carotid arteries was detected by Western blotting. The results are expressed as the mean ± SEM, n = 3. Statistical significance was determined using ANOVA by Student's t test. *P < 0.05 and **P < 0.01 vs. the control group