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. 2020 May 4;24(12):6750–6761. doi: 10.1111/jcmm.15326

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© 2020 The Authors. Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Clinical relevance of SOX3 in gastric cancer. A, Serum SOX3 level was higher in advanced cancer patients than in early cancer patients (P = .039). B, SOX was highly expressed in advanced gastric cancer tissues compared with that in early tumour. C, The overall survival (OS) of 304 gastric cancer patients was negatively associated with the SOX3 levels in tumour tissue (P = .0002). D, Stratified analyses indicated that the SOX3 levels in tumour tissues were correlated with the OSs in both patients of pTNM stage Ⅰ/Ⅱ (P = .016) and stage Ⅲ/Ⅳ (P = .015) conversely