TABLE 2.
Univariate and multivariate analyses for prognostic factors in gastric cancer patients (TCGA database) by the Cox model
| Characteristic | Univariate analysis (OS) | Multivariate analysis (OS) | ||
|---|---|---|---|---|
| HR (95% CI) | P‐value | HR (95% CI) | P‐value | |
| Gender (female vs male) | 1.30 (0.88‐1.93) | .186 | — | — |
| Age (>60 y vs ≤ 60 y) | 1.56 (1.05‐2.34) | .029 | 1.92 (1.27‐2.91) | .002 |
| Tumour location (upper vs middle vs lower) | 1.05 (0.85‐1.31) | .649 | — | — |
| Primary tumour invasion (T1 and T2 vs T3 and T4) | 1.41 (0.91‐2.19) | .121 | — | — |
| Lymph node metastasis (N0 vs N1‐3) | 1.75 (1.14‐2.68) | .011 | — | — |
| Distant metastasis (M0 vs M1) | 1.50 (0.73‐3.08) | .272 | — | — |
| pTNM stage (I and II vs III and IV) | 1.64 (1.13‐2.39) | .010 | 1.67 (1.14‐2.43) | .008 |
| SOX3 (>0.7 vs ≤0.7) | 2.13 (1.37‐3.31) | .001 | 1.85 (1.19‐2.88) | <.001 |
Abbreviations: HR, hazard ratio; OS, overall survival; TCGA, The Cancer Genome Atlas.