FIGURE 1.

POU4F3 mutations identified in the two Chinese families suffering from autosomal dominant hearing loss. A, Pedigrees of the Chinese families. Black squares and circles represent members with symptoms of DFNA15. The proband is indicated by an arrow. M and—indicate the mutant and wild‐type alleles, respectively. Asterisks indicate the families with POU4F3 mutations identified in the present study. B, Sanger sequencing showing the c.704_705del (p.T235fs) and the c.593G>A (p.R198H) mutations in POU4F3