HFD with different FA components induce mouse obesity. A, B, fatty acids composition in cocoa butter diet (A) and fish oil diet (B). C, mouse body weight on LFD (low fat diet, 10% fat), HFD (high-fat diet, 45%) cocoa butter diet or fish oil diet for 5 months (n=10/group). D, measurement of average food consumption of each mouse per day. E, F, quantification of total, subcutaneous and visceral fat in cocoa butter HFD- or fish oil HFD-induced obese mice by the MRI scanning. Representative MR images are shown in panel E. Average fat weight is shown in panel F. Data are shown as mean ± SD (**p<0.01, n.s., not significant).