Table 3.
Treatment groups for studying in vivo release profile of insulin.
| Group number | Treatment | Insulin dose (IU/kg) | Frequency of administration |
|---|---|---|---|
| I | Healthy control | - | - |
| II | Diabetic control | - | - |
| III | Free insulin solution | 0.5 IU/kg | Single |
| IV | Glargine | 0.5 IU/kg/day | Repeated every 24 h |
| V | Free insulin in thermosensitive copolymer solution | 45 IU/kg | Single |
| VI | CSO-Zinc insulin complexes in thermosensitive copolymer solution | 45 IU/kg | Single |
| VII | Oleic acid-g-CSO zinc insulin complexes in thermosensitive copolymer solution | 45 IU/kg | Single |