Table 6.
Summary of total cataract formation following STZ and insulin treatment in Sprague Dawley rats.
CATARACT FORMATION | ||||
---|---|---|---|---|
60 days | 90 days | |||
Group | one eye | both eyes | one eye | both eyes |
Healthy control | 0 | 0 | 0 | 0 |
Diabetic control (STZ) (untreated) | 1 | 4 | - | 6 |
Insulin solution | 3 | 2 | 1 | 5 |
Free Insulin in copolymeric depot | 4 | 1 | 2 | 4 |
CSO-Zinc-Insulin complex in copolymeric depot | 1 | 0 | 2 | 0 |
Oleic acid-g-CSO-Zinc-Insulin complex in copolymeric depot | 0 | 0 | 0 | 0 |
Glargine | 0 | 0 | 1 | 0 |