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. 2020 Jun 12;6(6):e04160. doi: 10.1016/j.heliyon.2020.e04160

Table 1.

Top 10 pharmaceutical products by Global sales in 2017 (million U.S. dollars).

Rank Product Therapeutic Subcategory Vendor Company Originator 2017 Sales ($m)
1 Humira Other anti-rheumatics AbbVie, Eisai Knoll 18,923
2 Enbrel Other anti-rheumatics Amgen, Pfizer, Takeda Immunex, acquired by Amgen 8,234
3 Revlimid Other cytostatics Celgene, BeiGene Celgene 8,211
4 Rituxan Anti-neoplastic MAbs Roche IDEC Pharmaceuticals, merged with Biogen 7,528
5 Remicade Other anti-rheumatics Johnson & Johnson, Merck & Co, Mitsubishi Tanabe Pharma Centocor, renamed Janssen Pharmaceutical 7,172
6 Herceptin Anti-neoplastic MAbs Roche Genentech 7,126
7 Avastin Anti-neoplastic MAbs Roche Genentech 6,795
8 Eylea Eye/Ophthalmic preparations Regeneron Pharmaceuticals, Bayer, Santen Pharmaceutical Regeneron Pharmaceuticals 6,291
9 Opdivo Anti-neoplastic MAbs Bristol-Myers Squibb, Ono Pharmaceutical Ono Pharmaceutical 5,761
10 Prevnar 13 Vaccines Pfizer Wyeth 5,693

Source: Evaluate Ltd. "Top 100 Products in 2024″