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Parkin levels are reduced in PARK2-mutated patients. (A) Representative western blot image of Parkin protein in primary skin fibroblasts of PARK2-mutated patients (P1, P2, P3, P4, and P5) and control subjects (C1, C2, C3, C4, and C5). (B) Relative quantification expressed as mean ± SEM (three technical replicates). Data were analyzed by two-tailed, unpaired Student’s t-test by comparison of PD patients and control subjects. **p < 0.001.
