FIGURE 9.

Evaluation of SmFES transcript levels of cercariae derived from Smfes-knocked-down eggs and the effects in the mammalian host infection outcome. (A) Bar graph depicting SmFES transcript levels mean in cercariae released from snails exposed to miracidia hatched from Smfes-knocked-down eggs. The dotted line represents normalized SmFES transcript levels in cercariae released from snails exposed to miracidia from control groups. Error bar is represented above the bars. Statistical analysis using Mann–Whitney test is represented with asterisks (N = 2, **P < 0.01). (B) Bar graph representing the percentage of mature (white), immature (gray), and dead (black) eggs in mice ileum after 42 days of cercariae infection. Statistical analysis of immature egg numbers using Mann–Whitney test is represented with asterisks above the bars (****P < 0.0001). (C) Bar graph representing the median length of adult worms recovered from mice infected with cercariae from controls group (gray) and from mice infected with Smfes-knocked-down cercariae (black). Above the bars are represented the 95% confidence interval. Statistical analysis using Mann–Whitney test is represented with asterisks (****P < 0.0001).