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Different concentrations of DILC siRNA and the scrambled control were administered to rats using the pre-implanted intrathecal catheter. (A) The expression of DILC in each group was measured by real-time qPCR. Pain threshold of rats to mechanical, thermal and cold stimulation were then measured: (B) thermal hyperalgesia; (C) thermal hyperalgesia; (D) cold hyperalgesia. N = 4, *P<0.05 vs. scrambled group.
