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. 2020 Jun 17;40(6):BSR20191062. doi: 10.1042/BSR20191062

Figure 3. Overexpression of Cosmc could inhibit proliferation, migration and invasion of BC cells while promoting cell apoptosis.

Figure 3

(A and B) The relative protein levels of Ki67, PCNA, Bax, and Bad to the internal reference GAPDH in BC cell lines as determined by Western blot. (C and D) The cell proliferation of BC cell lines followed lentiviral vector infection as evaluated by EdU staining (×200). (E and F) The cell migration of BC cell lines following lentiviral vector infection as assessed by a scratch test (×100). (G and H) The cell invasion of BC cell lines following lentiviral vector infection as determined by Transwell assay (×200). (I and J) The cell apoptosis of BC cell lines following lentiviral vector infection as examined by flow cytometry; *P<0.05 vs. the sh-NC group or the oe-NC group. Data were measurement data and displayed as mean ± standard deviation; data comparison between two groups was evaluated by non-paired t-test. The experiments were repeated three times.