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(a) Superimposition of the lateral interacting αβ tubulin dimers at the top of neighboring MT PFs for the GTP (green) and GDP (cyan) states. The M-loop, which is crucial for lateral interactions, is shown in yellow. (b and c) Shown is a magnified view of the lateral interactions formed between the M-loop and the other side for GTP (b) and GDP (c) states. Key residues K60, Q85, R88, P89, and Y283 are shown using “sticks” representation in PyMol. To see this figure in color, go online.
