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APG‐1252‐M1 exhibited synergy with chemotherapeutic drugs in vitro. Compared with the single treatments and control, the APG‐1252‐M1 plus 5‐FU treatment led to a higher rate of apoptosis in AGS and N87 (A, B; * P < .05). (C) Western blot showed that compared to the any single treatment, the combined treatment led to increased expression of the cleaved caspase 3 and PARP‐1 protein in AGS and N87
