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. 2020 Apr 23;9(12):4207–4231. doi: 10.1002/cam4.3077

Table 2.

Summary of simple microfluidic systems

System Cell lines Cancer types MNPs Q (mL/h) η (%) Clinical validation References
Magnetic sifter H1650 Non‐small cell lung SA‐coated 10 91.4 Yes [90]
MCF7/HCC827 Breast/non‐small cell lung Conventional Yes [91]
Microwells THP1 Leukemia Grouped 3 62 No [92]
M6C Mouse breast SA‐coated 1.2 ~90 No [93]
HCT116 Colorectal SA‐coated 0.54 92 No [94]
Hep3B Hepatocellular carcinoma SA‐coated 1.5 ~90 No [95]
Magnet COlO205/SKBR3 Colorectal/breast Conventional 10 90 No [96]
  SKBR3/PC3/COlO205 Breast/prostate/colorectal Conventional 2.5 >90 Yes [97]
Micropatterns SKBR3 Breast Conventional 5 ~90 Yes [88]
MCF7 Breast Conventional 2.4 ~93 No [98]
COlO205 Colorectal Conventional 2.5 69.1 No [99]
MCF7 Breast Conventional 0.02 90.8 No [100]
COlO205 Colorectal Conventional 2.5 95.6 No [101]
RAW 264.7 Mouse leukemic macrophage SA‐coated >90 No [102]
SUM149 Breast SA‐coated 3 No [89]