TABLE 1.
Performance of each model possibility by case‐control study
Markers included in the model | Performance index | |||||
---|---|---|---|---|---|---|
AIC | BIC | RMSE | AUC | R 2 | P‐value | |
CXCL13 | 64.4 | 70.2 | 0.236 | 0.979 | .682 | <.0001 |
IL‐10 | 41.6 | 47.4 | 0.185 | 0.971 | .802 | <.0001 |
β2‐MG | 91.0 | 96.8 | 0.297 | 0.927 | .542 | <.0001 |
sIL‐2R | 149.0 | 154.8 | 0.398 | 0.845 | .236 | <.0001 |
CXCL13 + IL‐10 | 23.6 | 32.3 | 0.137 | 0.998 | .908 | <.0001 |
CXCL13 + β2‐MG | 41.8 | 50.5 | 0.190 | 0.990 | .812 | <.0001 |
CXCL13 + sIL‐2R | 59.1 | 67.8 | 0.230 | 0.984 | .721 | <.0001 |
IL‐10 + β2‐MG | 38.0 | 46.7 | 0.163 | 0.978 | .832 | <.0001 |
IL‐10 + sIL‐2R | 43.5 | 52.2 | 0.186 | 0.978 | .803 | <.0001 |
β2‐MG + sIL‐2R | 90.1 | 98.8 | 0.289 | 0.935 | .557 | <.0001 |
CXCL13 + IL‐10 + β2‐MG | 24.1 | 35.6 | 0.135 | 0.998 | .917 | <.0001 |
CXCL13 + IL‐10 + sIL‐2R | 25.7 | 37.2 | 0.137 | 0.998 | .908 | <.0001 |
CXCL13 + β2‐MG + sIL‐2R | 43.8 | 55.4 | 0.191 | 0.990 | .813 | <.0001 |
IL‐10 + β2‐MG + sIL‐2R | 40.1 | 51.6 | 0.162 | 0.978 | .832 | <.0001 |
CXCL13 + IL‐10 + β2‐MG + sIL‐2R | 25.9 | 40.3 | 0.134 | 0.998 | .919 | <.0001 |
Bold indicates highest or lowest value.
Abbreviations: AIC, Akaike information criterion; AUC, the area under the ROC curve; BIC, Bayesian information criterion; R 2, R‐squared; RMSE, root mean squared error.