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. 2020 Apr 20;9(12):4114–4125. doi: 10.1002/cam4.3048

TABLE 1.

Performance of each model possibility by case‐control study

Markers included in the model Performance index
AIC BIC RMSE AUC R 2 P‐value
CXCL13 64.4 70.2 0.236 0.979 .682 <.0001
IL‐10 41.6 47.4 0.185 0.971 .802 <.0001
β2‐MG 91.0 96.8 0.297 0.927 .542 <.0001
sIL‐2R 149.0 154.8 0.398 0.845 .236 <.0001
CXCL13 + IL‐10 23.6 32.3 0.137 0.998 .908 <.0001
CXCL13 + β2‐MG 41.8 50.5 0.190 0.990 .812 <.0001
CXCL13 + sIL‐2R 59.1 67.8 0.230 0.984 .721 <.0001
IL‐10 + β2‐MG 38.0 46.7 0.163 0.978 .832 <.0001
IL‐10 + sIL‐2R 43.5 52.2 0.186 0.978 .803 <.0001
β2‐MG + sIL‐2R 90.1 98.8 0.289 0.935 .557 <.0001
CXCL13 + IL‐10 + β2‐MG 24.1 35.6 0.135 0.998 .917 <.0001
CXCL13 + IL‐10 + sIL‐2R 25.7 37.2 0.137 0.998 .908 <.0001
CXCL13 + β2‐MG + sIL‐2R 43.8 55.4 0.191 0.990 .813 <.0001
IL‐10 + β2‐MG + sIL‐2R 40.1 51.6 0.162 0.978 .832 <.0001
CXCL13 + IL‐10 + β2‐MG + sIL‐2R 25.9 40.3 0.134 0.998 .919 <.0001

Bold indicates highest or lowest value.

Abbreviations: AIC, Akaike information criterion; AUC, the area under the ROC curve; BIC, Bayesian information criterion; R 2, R‐squared; RMSE, root mean squared error.