TABLE 1.
Sex | Age | Time post‐LT | Location of management | Symptoms | Interstitial pneumonia | Treatment | Baseline IS | Changes to IS | Outcome | |
---|---|---|---|---|---|---|---|---|---|---|
Patient 1 a | M | 69 | 5 d | Ward | Fever, dry cough | No | HCQ | Tac + MMF +Pred | ↓MMF | Alive |
Patient 2 a | M | 59 | 8 mo | Ward | Mild dyspnea, diarrhea | Yes | HCQ, O2 | Tac + Eve | None | Alive |
Patient 3 a | M | 56 | 3 y3 mo | Ward | Sore throat, dry cough, fever | Yes | HCQ, O2 | Tac + Eve | Stop Tac | Alive |
Patient 4 | M | 58 | 2 mo | Home | None | No | None | Tac + MMF +Pred | None | Alive |
Patient 5 | F | 64 | 4a4 mo | Ward | Fever, lack of appetite, diarrhea | Yes | Steroids, O2 | Tac + Pred | ↑Pred | Alive |
Patient 6 | M | 64 | 8a | Ward | Fever | Yes | HCQ, O2, CPAP | Tac + MMF | Stop MMF, ↓Tac | Alive |
Patient 7 | M | 64 | 9 y3 mo | Ward | Fever | Yes |
LPV/RTV, HCQ, O2 |
Tac + MMF | Stop Tac | Alive |
Patient 8 | M | 62 | 11a | Ward | Fever | Yes | DRV/RTV, HCQ, steroids, O2 | Tac + MMF | Stop Tac | Dead b |
Patient 9 | M | 75 | 11a8 mo | Ward | Diarrhea, myalgia, fever, cough | Yes | Steroids, O2, CPAP | Tac + MPA | Stop MPAStop Tac | Dead |
Patient 10 | F | 85 | 22a7 mo | Ward c | None | No | None | Tac | None | Alive |
Abbreviations: CPAP, continuous positive airway pressure; DRV/RTV, darunavir/ritonavir; Eve, everolimus; HCQ, hydroxycholoroquine; IS, immunosuppression; LPV/RTV, lopinavir/ritonavir; LT, liver transplantation; MMF, mycophenolate mofetil; MPA, mycophenolic acid; Pred, prednisone; Tac, tacrolimus.
Cases of the first three patients are reported in detail in the manuscript.
Deceased for unrelated cause after negative COVID‐19 test.
Patient admitted for rectus abdomins abscess, accidentally diagnosed with SARS‐CoV‐2 infection during admission.