FIGURE 1.
Potential mechanisms by which Curcumin and Zinc can exert therapeutic effects against COVID‐19. Curcumin inhibits SARS‐CoV‐2 entry by binding directly to the receptor‐binding domain (RBD) of spike (S) protein of the virus. Whereas, Zn2+ causes inhibition of RNA‐dependent RNA‐polymerase (RdRp) and reduction in template binding [Colour figure can be viewed at wileyonlinelibrary.com]