Table 1.

Haematological postoperative protocol used in this patient

Days postsurgery	FVIII levels	Dose guidelines
+1	92.3%	40 IU/kg/8 h
+3	FVIIIb: 60% Cmax FVIII: 170%	40 IU/kg/12 h
+6	FVIIIb: 89% Cmax FVIII:159%	25 IU/kg/12 h
+9	FVIIIb: 55% Cmax FVIII:111%	25 IU/kg/12 h
+13	FVIIIb: 43% Cmax FVIII:110%	37 IU/kg/24 h
+16	FVIIIb: 21% Cmax FVIII:139%	37 IU/kg/48 h

FVIIIb: level FVIII before infusion, Cmax FVIII 20 min after infusion