Table 3.
Comparison of clinical features and outcomes between the treatment (Convalescent Plasma) group and the control (non‐convalescent plasma) group (modified from [15,16,25]).
| CCP treatment group (n = 19) | Control (Non‐CCP) group (n = 10) | P value | |
|---|---|---|---|
| Demographics | |||
| Age, years | 55.00 (46.00–67.00) | 53.00 (46.50–60.50) | 0.743 |
| Gender | |||
| Male | 11 (58) | 6 (60) | 1.000 |
| Female | 8 (42) | 4 (40) | |
| Comorbidity | |||
| Yes | 13 (68) | 6 (60) | 0.698 |
| No | 6 (32) | 4 (40) | |
| Laboratory test parameters | |||
| C‐reactive protein | 65.02 (29.50–157.85) | 96.70 (33.92–173.39) | 0.7088 |
| Lymphocyte a | 0.65 (0.53–0.90) | 0.76 (0.54–1.32) | 0.469 |
| SaO2 a | 93.00 (89.00–96.50) | 93.00 (87.50–97.50) | 0.923 |
| Clinical outcome | |||
| Death | 0 (0) | 3(30) | ＜0.001* |
| Stable | 2 (10) | 6(60) | |
| Improved | 8 (42) | 1(10) | |
| Discharged | 9 (48) | 0(0) | |
Continuous variable (age) is expressed as median (IQR) and compared with Mann–Whitney U test. Categorical data are n (%) of patients, where n is the total number of patients with available data, and compared with Fisher’s exact test between convalescent plasma treatment group and control group. SaO2, oxyhaemoglobin saturation. Reference ranges are as follows: C‐reactive protein, normal range ＜ 8 mg/l; lymphocyte count, 1.2–3.4 × 109/l; SaO2 %, normal range ≥ 95%.
Among the 19 patients in CP treatment group, nine patients did not have their blood lymphocyte and SaO2 data available.
P < 0.001, Fisher’s exact test.