Table 1.
Characteristics of patients with bullous pemphigoid and pemphigus vulgaris
| Bullous pemphigoid (n = 62) | Pemphigus vulgaris (n = 31) | |||||
| Suspected COVID‐19 symptoms (n = 10) | Asymptomatic (n = 52) | P‐value | Suspected COVID‐19 symptoms (n = 7) | Asymptomatic (n = 24) | P‐value | |
| Age (years), mean ± SD (range) | 79·5 ± 11·2 (61–98) | 78·0 ± 10·2 (52–95) | 0·70 | 68·3 ± 9·7 (60–87) | 60·0 ± 17·7 (19–95) | 0·30 |
| Age at onset (years), mean ± SD (range) | 75·4 ± 10·1 (57–89) | 75·7 ± 10·2 (51–94) | 0·94 | 53·1 ± 12·7 (35–71) | 52·4 ± 16·8 (11–93) | 0·91 |
| Duration of disease (months), mean ± SD (range) | 48·4 ± 40·6 (13–113) | 28·2 ± 26·5 (1–123) | 0·04 | 181·9 ± 146·1 (15–411) | 101·1 ± 81·1 (5–267) | 0·07 |
| Male | 60 (6/10) | 54 (28/52) | 0·72 | 14 (1/7) | 67 (16/24) | 0·02 |
| Contact with person with suspected or confirmed COVID‐19 | 70 (7/10) | 2 (1/52) | < 0·001 | 29 (2/7) | 8 (2/24) | 0·16 |
| Principal comorbidities | ||||||
| Diabetes | 30 (3/10) | 37 (19/52) | 0 (0/7) | 13 (3/24) | ||
| Hypertension | 30 (3/10) | 27 (14/52) | 14 (1/7) | 0 (0/24) | ||
| Neurological or psychiatric diseases | 30 (3/10) | 21 (11/52) | 29 (2/7) | 13 (3/24) | ||
| Cardiovascular diseases | 30 (3/10) | 35 (18/52) | 0 (0/7) | 8 (2/24) | ||
| Chronic kidney failure | 30 (3/10) | 6 (3/52) | 0 (0/7) | 0 (0/24) | ||
| Dyslipidemia | 20 (2/10) | 13 (7/52) | 14 (1/7) | 0 (0/24) | ||
| Neoplasia | 10 (1/10) | 6 (3/52) | 14 (1/7) | 4 (1/24) | ||
| Therapy | ||||||
| Systemic steroid | 60 (6/10) | 88 (46/52) | 0·03 | 57 (4/7) | 75 (18/24) | 0·36 |
| Dosage (mg per day), mean ± SDa | 5·2 ± 1·7 | 6·0 ± 3·6 | 0·56 | 5·9 ± 6·2 | 5·6 ± 4·9 | 0·91 |
| Azathioprine | 0 (0/10) | 8 (4/52) | 0·36 | 14 (1/7) | 8 (2/24) | 0·64 |
| Doxycycline | 0 (0/10) | 12 (6/52) | 0·26 | – | – | – |
| Cyclophosphamide | – | – | – | 0 (0/7) | 17 (4/24) | 0·34 |
| Dapsone | – | – | – | 0 (0/7) | 8 (2/24) | 0·59 |
The data are presented as % (n/N) unless stated otherwise. Means and SDs were compared between patients using a t‐test for independent samples. Categorical variables were summarized as the number and percentage of all patients and were evaluated using the χ2‐test or Fisher's exact test. Significance was set at P < 0·05. aPrednisone or equivalent.