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. 2020 Jun 18;51(7):645–653. doi: 10.1016/j.arcmed.2020.06.011

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© 2020 IMSS. Published by Elsevier Inc.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Panel A depict circos plot from the peripheral blood mononuclear cells transcriptome from COVID-19 patients. Inner ring is the scatter plot representing each transcript identified followed by chromosome number and size, the outer ring present genes identified participating in G1/S transition of mitotic cell cycle and protein processing. B and C panels show Gene Ontology at biological process and molecular function terms, respectively, from top 100 up-regulated genes. D and E panels show Gene Ontology at biological process and molecular function terms, respectively, from top 100 down-regulated genes.

Panel A depict circos plot from the peripheral blood mononuclear cells transcriptome from COVID-19 patients. Inner ring is the scatter plot representing each transcript identified followed by chromosome number and size, the outer ring present genes identified participating in G1/S transition of mitotic cell cycle and protein processing. B and C panels show Gene Ontology at biological process and molecular function terms, respectively, from top 100 up-regulated genes. D and E panels show Gene Ontology at biological process and molecular function terms, respectively, from top 100 down-regulated genes.