The comparisons with the relative expressions of myocardial protein TXNIP, TRX, NF-ĸBp65, NLRP3, and Caspase-1 in each group rats (n = 8, ). (a) Ratio of TXNIP/β-actin in rats' myocardium; (b) ratio of TRX/β-actin in rats' myocardium; (c) ratio of NF-ĸBp65/β-actin in rats' myocardium; (d) ratio of NLRP3/β-actin in rats' myocardium; and (e) ratio of Caspase-1/β-actin in rats' myocardium. β-Actin: protein internal reference; TXNIP: thioredoxin-interacting protein; TRX: thioredoxin protein; NF-ĸBp65: nuclear transcription factor kappa Bp65; NLRP3; NLRP3 inflammatory; and Caspase-1: cysteinaspartate specific proteinase 1. A: the control group, B: the exhaustive exercise group, C: the low-intensity exercise preconditioning + exhaustive exercise group, D: the middle-intensity exercise preconditioning + exhaustive exercise group, and E: the group intense exercise preconditioning + exhaustive exercise group.∗P < 0.05, compared with the CON group; #P < 0.05, compared with the EE group; ΔP < 0.05, compared with the LEP + EE group.