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. 2020 Mar 5;10(2):209–223. doi: 10.1016/j.jcmgh.2020.02.007

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© 2020 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Metabolic pathways are affected in regenerating Hnf4a knockout mice. (A) Principal component analysis of microarray data from small-intestinal tissue of VillinCreERT2^--Hnf4a^fl/fl and VillinCreERT2⁺-Hnf4a^fl/fl mice 96 hours after irradiation. (B) Heatmap showing the top 50 up-regulated and down-regulated genes from the microarray. (C) Log(P value) of pathway analysis (KEGG pathways). n = 8 per group. KEGG, Kyoto Encyclopedia of Genes and Genomes; PC, principal component.