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. Author manuscript; available in PMC: 2021 Jan 15.
Published in final edited form as: Int J Cancer. 2019 Jul 4;146(2):363–372. doi: 10.1002/ijc.32516

Table 2.

htSNPs with the lowest p-values for the association with risk of colon cancer, grouped by gene

Colon (proximal+distal)
ht SNP ID OR (95% CI) p-value for SNP effect BSGoF-Adjusted
p-value
ATM(DSBR)
rs11212592 0.92 (0.87–0.97) 3.30X10−03 0.021
rs61915066 1.13 (1.04–1.24) 4.81X10−03 0.021
EXO1 (MMR, EPN)
rs4658549 1.06 (1.02–1.11) 5.33X10−03 0.021
FANCA (DCLR)
rs2238526 0.94 (0.91–0.98) 3.98X10−03 0.021
rs3743861 0.94 (0.91–0.98) 6.13X10−03 0.021
FANCE (DCLR)
rs6907678 0.94 (0.90–0.98) 1.79X10−03 0.020
rs10947550 0.94 (0.90–0.98) 2.32X10−03 0.020
FEN1(BER, EPN)
rs4246215 0.93 (0.89–0.97) 1.59X10−03 0.020
LIG1(NER,BER)
rs1971775 1.06 (1.02–1.11) 4.38X10−03 0.021
rs73054038 0.92 (0.87–0.98) 5.32X10−03 0.021
MLH1 (MMR)
rs1800734 1.13 (1.07–1.18) §3.48X10−06 0.019
rs6784088 0.94 (0.90–0.98) 3.28X10−03 0.020
rs9855475 0.94 (0.90–0.98) 3.42X10−03 0.021
PMS2 (MMR)
rs12112229 1.07 (1.02–1.13) 3.15X10−03 0.020
RBBP8 (HR)
rs113047993 1.15 (1.07–1.25) 2.36X10−04 0.019
TP53BP1 (NHEJ)
rs17782975 0.88 (0.82–0.96) 1.91X10−03 0.020
§

statistically significant after Bonferroni’s correction