Table 2.
Colon (proximal+distal) | |||
---|---|---|---|
ht SNP ID | OR (95% CI) | p-value for SNP effect | BSGoF-Adjusted p-value |
ATM(DSBR) | |||
rs11212592 | 0.92 (0.87–0.97) | 3.30X10−03 | 0.021 |
rs61915066 | 1.13 (1.04–1.24) | 4.81X10−03 | 0.021 |
EXO1 (MMR, EPN) | |||
rs4658549 | 1.06 (1.02–1.11) | 5.33X10−03 | 0.021 |
FANCA (DCLR) | |||
rs2238526 | 0.94 (0.91–0.98) | 3.98X10−03 | 0.021 |
rs3743861 | 0.94 (0.91–0.98) | 6.13X10−03 | 0.021 |
FANCE (DCLR) | |||
rs6907678 | 0.94 (0.90–0.98) | 1.79X10−03 | 0.020 |
rs10947550 | 0.94 (0.90–0.98) | 2.32X10−03 | 0.020 |
FEN1(BER, EPN) | |||
rs4246215 | 0.93 (0.89–0.97) | 1.59X10−03 | 0.020 |
LIG1(NER,BER) | |||
rs1971775 | 1.06 (1.02–1.11) | 4.38X10−03 | 0.021 |
rs73054038 | 0.92 (0.87–0.98) | 5.32X10−03 | 0.021 |
MLH1 (MMR) | |||
rs1800734 | 1.13 (1.07–1.18) | §3.48X10−06 | 0.019 |
rs6784088 | 0.94 (0.90–0.98) | 3.28X10−03 | 0.020 |
rs9855475 | 0.94 (0.90–0.98) | 3.42X10−03 | 0.021 |
PMS2 (MMR) | |||
rs12112229 | 1.07 (1.02–1.13) | 3.15X10−03 | 0.020 |
RBBP8 (HR) | |||
rs113047993 | 1.15 (1.07–1.25) | 2.36X10−04 | 0.019 |
TP53BP1 (NHEJ) | |||
rs17782975 | 0.88 (0.82–0.96) | 1.91X10−03 | 0.020 |
statistically significant after Bonferroni’s correction