Table 2. Cardiovascular Death and Sudden Cardiac Death After Azithromycin and Amoxicillin Exposure.
Mortality | Azithromycin (n = 1 736 976) | Amoxicillin (n = 6 087 705) | Adjusted | |||
---|---|---|---|---|---|---|
Deaths, No. | Cumulative incidencea | Deaths, No. | Cumulative incidencea | Risk difference (95% CI)a,b | Hazard ratio (95% CI)b | |
Cardiovascular, d | ||||||
0-5 | 62 | 35.91 | 95 | 15.68 | 12.79 (3.66 to 26.21) | 1.82 (1.23 to 2.67) |
6-10 | 31 | 18.34 | 68 | 11.41 | 3.15 (−2.31 to 11.91) | 1.28 (0.80 to 2.04) |
Sudden cardiac, d | ||||||
0-5 | 21 | 12.17 | 39 | 6.44 | 3.83 (−0.63 to 11.70) | 1.59 (0.90 to 2.81) |
6-10 | 16 | 9.47 | 36 | 6.04 | 4.04 (−3.82 to 19.04) | 1.32 (0.69 to 2.52) |
Per 1 000 000 prescriptions.
Adjusted for propensity score decile, age, and sex.