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. 2020 Jun 17;3(6):e208199. doi: 10.1001/jamanetworkopen.2020.8199

Table 2. Cardiovascular Death and Sudden Cardiac Death After Azithromycin and Amoxicillin Exposure.

Mortality Azithromycin (n = 1 736 976) Amoxicillin (n = 6 087 705) Adjusted
Deaths, No. Cumulative incidencea Deaths, No. Cumulative incidencea Risk difference (95% CI)a,b Hazard ratio (95% CI)b
Cardiovascular, d
0-5 62 35.91 95 15.68 12.79 (3.66 to 26.21) 1.82 (1.23 to 2.67)
6-10 31 18.34 68 11.41 3.15 (−2.31 to 11.91) 1.28 (0.80 to 2.04)
Sudden cardiac, d
0-5 21 12.17 39 6.44 3.83 (−0.63 to 11.70) 1.59 (0.90 to 2.81)
6-10 16 9.47 36 6.04 4.04 (−3.82 to 19.04) 1.32 (0.69 to 2.52)
a

Per 1 000 000 prescriptions.

b

Adjusted for propensity score decile, age, and sex.