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. 2020 Jun 9;2020:9467359. doi: 10.1155/2020/9467359

Table 4.

Effect of B. abyssinica crude extract and aqueous fraction on percentage parasitemia, and survival time of P. berghei-infected mice in Rane's test.

Group % parasitemia (±SEM) % suppression MST (days)
D3 D4 D5 D6 D7
DW 10 ml/kg 21.63 ± 0.33 23.72 ± 0.68 25.27 ± 1.61 27.12 ± 0.78 29.68 ± 0.82 0.00 8.17 ± 0.48
BA 100 mg/kg 24.01 ± 0.48 24.30 ± 0.70 22.67 ± 0.92b3 21.57 ± 1.64b3 19.95 ± 1.42a3,b3 34.37a3,b3 13.29 ± 1.41b3
BA 200 mg/kg 24.92 ± 0.83 24.07 ± 1.00 23.42 ± 1.36b3 22.05 ± 2.91b3 16.86 ± 1.08a3,b3 43.19a3,b3 14.50 ± 1.82a2,b3
BA 400 mg/kg 25.05 ± 0.75 24.13 ± 0.76 21.87 ± 0.59b3 19.75 ± 0.99b3 12.48 ± 0.77a3,b3,c3,d1 57.94a3,b3,c3,d1 16.67 ± 0.49a3,b3
AQ 100 mg/kg 24.88 ± 0.62 26.06 ± 0.65b3 24.78 ± 0.90b3 22.12 ± 0.89b3 19.87 ± 0.56a3,b3 31.40a3,b3 11.60 ± 1.44b3
AQ 200 mg/kg 24.73 ± 0.97 24.67 ± 0.97b1 22.12 ± 0.64b3 21.60 ± 1.34b3 17.58 ± 1.44a3,b3 40.77a3,b3 13.83 ± 1.60a1,b3
AQ 400 mg/kg 25.18 ± 0.80 24.03 ± 0.91b1 22.87 ± 1.22b3 20.92 ± 1.59b3 14.36 ± 1.23a3,b3,e2 51.62a3,b3,e2 15.17 ± 1.87a2,b3
CQ 25 mg/kg 22.68 ± 0.78 20.47 ± 1.07a1 13.72 ± 1.51a3 5.28 ± 2.42a3 0.00 ± 0.00a3 100.00a3 30.00 ± 0.00a3

Data are expressed as mean ± SEM; n = 6, a = compared to DW, b = compared to CQ 25 mg/kg, c = compared to BA 100 mg/kg, d = compared to BA 200 mg/kg, e = compared to AQ 100 mg/kg, 1 = P < 0.05, 2 = P < 0.01, 3 = P < 0.001, DW = distilled water, BA = Bersama abyssinica crude extract, AQ = aqueous fraction, CQ = chloroquine, SEM = standard error of mean, MST = mean survival time, D3 = day 3, D4 = day 4, D5 = day 5, D6 = day 6, and D7 = day 7.