Figure 2.

Further intervention of acupuncture on inflammation responses after regulating NF-κB. ^∗Acupuncture could inhibit the activation of NF-κB and further regulates inflammatory cells and inflammatory cytokines to relieve inflammatory response in this review. Inflammation cells include Th17 and Treg cells, macrophages 1 and macrophages 2 cells, and mast cells. Inflammatory cytokines include IL-1, IL-1β, IL-6, IL-10, IL-12, IL-13, TNF-α, and MCP-1. These inflammation factors have pro- or anti-inflammation function. After downregulation of NF-κB by acupuncture, these inflammatory factors present a tendency of anti-inflammation.