CMAX of MS. Comparison of mean (±SD) CMAX for plasma morphine during 540 minutes of blood sampling time between normal-weight, non-OSAS controls, nonobese OSAS, and obese patients with OSAS. Dose-adjusted mean CMAX in obese patients with OSAS is also presented. *P < .05 versus the nonobese/non-OSAS control group. CMAX indicates maximum concentration; MS, morphine sulfate; OSAS, obstructive sleep apnea syndrome; SD, standard deviation.