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. 2020 Jun 18;11:51. doi: 10.1186/s13229-020-00353-2

Table 2.

Models for primary sample. Uncorrected p-values are reported. One outlier was removed from the lateral ventricle model.

CHOP Models
Predictors Estimates std. Beta p partial η2 Estimates std. Beta p partial η2 Estimates std. Beta p partial η2
TBV GMV WMV
Intercept 1034.67 -0.35 <0.001 0.69 698.45 -0.34 <0.001 0.77 337.69 -0.29 <0.001 0.48
IQ 1.52 0.25 <0.001 0.07 0.90 0.25 <0.001 0.08 0.62 0.20 <0.001 0.04
Age -1.80 -0.06 0.143 0.00 -6.13 -0.33 <0.001 0.15 4.29 0.27 <0.001 0.09
Sex 85.43 0.73 <0.001 0.20 48.28 0.69 <0.001 0.21 37.13 0.62 <0.001 0.15
Diagnosis -206.92 -0.25 <0.001 0.05 -130.81 -0.27 <0.001 0.07 -75.89 -0.17 <0.001 0.03
IQ*Diagnosis 1.67 0.28 <0.001 0.04 1.05 0.29 <0.001 0.05 0.62 0.20 0.001 0.02
R2 / R2 adjusted 0.290 / 0.282 0.377 / 0.370 0.280 / 0.272
Cortical GMV Cortical WMV
Intercept 532.98 -0.33 <0.001 0.72 314.27 -0.30 <0.001 0.47
IQ 0.75 0.25 <0.001 0.07 0.61 0.21 <0.001 0.05
Age -5.66 -0.36 <0.001 0.17 3.80 0.26 <0.001 0.08
Sex 38.27 0.64 <0.001 0.18 35.57 0.63 <0.001 0.16
Diagnosis -112.55 -0.26 <0.001 0.07 -72.09 -0.17 <0.001 0.03
IQ*Diagnosis 0.91 0.30 <0.001 0.06 0.59 0.20 0.001 0.02
R2 / R2 adjusted 0.370 / 0.363 0.276 / 0.268
Cerebellum Cerebellar GMV Cerebellar WMV
Intercept 128.62 -0.27 <0.001 0.66 105.20 -0.27 <0.001 0.68 23.42 -0.15 <0.001 0.35
IQ 0.13 0.17 <0.001 0.03 0.11 0.19 <0.001 0.04 0.02 0.06 0.178 0.00
Age 0.01 0.00 0.929 0.00 -0.48 -0.16 <0.001 0.03 0.49 0.37 <0.001 0.14
Sex 8.50 0.58 <0.001 0.12 6.94 0.59 <0.001 0.13 1.57 0.31 <0.001 0.04
Diagnosis -15.91 -0.23 0.004 0.02 -12.11 -0.26 0.005 0.02 -3.80 -0.08 0.046 0.01
IQ*Diagnosis 0.12 0.16 0.020 0.01 0.09 0.14 0.029 0.01 0.03 0.12 0.065 0.01
R2 / R2 adjusted 0.176 / 0.167 0.213 / 0.204 0.189 / 0.180
Lateral Ventricles Third Ventricles GMV:WMV Ratio
Intercept 7.28 -0.04 <0.001 0.03 0.75 -0.05 <0.001 0.14 1.93 0.05 <0.001 0.87
IQ -0.01 -0.02 0.669 0.00 -0.00 -0.00 0.993 0.00 -0.00 -0.02 0.564 0.00
Age 0.28 0.19 <0.001 0.03 0.00 0.01 0.827 0.00 -0.03 -0.67 <0.001 0.46
Sex 0.49 0.08 0.288 0.00 0.03 0.12 0.119 0.01 -0.02 -0.13 0.033 0.01
Diagnosis -0.83 -0.14 0.042 0.01 0.09 -0.20 0.148 0.00 -0.01 -0.05 0.334 0.00
Age*Diagnosis -0.01 -0.16 0.017 0.01
R2 / R2 adjusted 0.049 / 0.040 0.040 / 0.029 0.464 / 0.459