Table 1. Characterization of Chemical Constituents in FZK by HPLC–MSa.
| no. | tR (min) | detected ion (m/z) | formula | identity | source |
|---|---|---|---|---|---|
| 1 | 2.659 | [M + H] + 118.1 | C8H7N | indole | BJT |
| 2 | 2.912 | [M + H] + 116.1 | C5H9NO2 | (2S)-pyrrolidin-1-ium-2-carboxylate | BZ |
| 3 | 3.777 | [M – H] – 173.1 | C6H14N4O2 | protonated arginine | BZ |
| 4 | 4.408 | [M – H] – 549.3 | C32H38O8 | 6,6′-dimethoxygossypol | DS |
| 5 | 6.265 | [M – H] – 191.1 | C10H8O4 | scopoletin | BZ |
| 6 | 6.265 | [M – H] – 191.1 | C11H12O3 | myristicin | DS |
| 7 | 7.149 | [M – H] – 298.1 | C19H38O2 | methyl stearate | DS |
| 8 | 7.401 | [M – H] – 581.3 | C26H30O15 | asperuloside tetraacetate | BJT |
| 9 | 7.437 | [M + H] + 132.1 | C6H13NO2 | (2S,3S)-2-ammonio-3-methylpentanoate | BZ |
| 10 | 9.096 | [M + H] + 182.1 | C13H11N | 3-methyl-9H-carbazole | DS |
| 11 | 9.547 | [M + H] + 182.1 | C9H11NO3 | tyrosine | BZ |
| 12 | 9.961 | [M – H] – 665.3 | C24H42O21 | nystose | BJT |
| 13 | 12.251 | [M – H] – 389.2 | C24H38O4 | diisooctyl phthalate | DS |
| 14 | 12.305 | [M – H] – 389.2 | C25H26O4 | hispaglabridin B | GC |
| 15 | 12.954 | [M – H] – 827.4 | C30H52O26 | 1F-fructofuranosylnystose | BJT |
| 16 | 13.747 | [M + H] + 268.1 | C10H13N5O4 | adenosine | FF /DS |
| 17 | 14.631 | [M + H] + 166.1 | C9H11NO2 | (2S)-2-azaniumyl-3-phenylpropanoate | BZ |
| 18 | 16.437 | [M + H] + 254.2 | C13H19NO4 | codonopsinol B | DS |
| 19 | 16.921 | [M + H] + 268.2 | C14H21NO4 | codonopsine | DS |
| 20 | 19.357 | [M + H] + 205.1 | C11H12N2O2 | tryptophan | DS |
| 21 | 21.049 | [M + H] – 209.1 | C15H30 | 1-pentadecene | DS |
| 22 | 21.103 | [M – H] – 419.2 | C25H24O6 | gancaonin H | GC |
| 23 | 21.103 | [M – H] – 419.2 | C25H24O6 | morusin | GC |
| 24 | 22.365 | [M + H] + 217.2 | C15H20O | atractylon | BZ |
| 25 | 26.476 | [M + H] + 469.2 | C22H28O11 | prim-O-glucosylcimifugin | FF |
| 26 | 28.82 | [M – H] – 549.3 | C26H30O13 | licraside | GC |
| 27 | 28.871 | [M + H] + 257.1 | C15H12O4 | liquiritigenin | GC |
| 28 | 29.126 | [M – H] – 417.2 | C22H26O8 | episyringaresinol | DS |
| 29 | 29.667 | [M – H] + 307.2 | C16H18O6 | cimifugin | FF |
| 30 | 30.749 | [M + H] + 453.2 | C22H28O10 | 5-O-methylvisammioside | FF |
| 31 | 35.851 | [M + H] + 291.2 | C16H18O5 | 5-O-methylvisamminol | FF |
| 32 | 36.987 | [M + H] + 439.2 | C21H26O10 | sec-o-glucosylhamaudol | FF |
| 33 | 37.113 | [M + H] + 439.2 | C27H34O5 | 5-O-methyllicoricidin | GC |
| 34 | 41.044 | [M – H] – 514.4 | C31H46O6 | poricoic acid D | FL |
| 35 | 41.979 | [M – H] – 837.5 | C42H62O17 | licorice saponin G2 | GC |
| 36 | 43.784 | [M + H] + 373.3 | C17H24O9 | tangshenosideII | DS |
| 37 | 45.443 | [M – H] – 498.4 | C31H46O5 | poricoic acid A | FL |
| 38 | 46.344 | [M + H] – 821.5 | C34H46O23 | citrifolinin A-1 | BJT |
| 39 | 49.062 | [M – H] – 407.3 | C20H24O9 | ammijin | FF |
| 40 | 49.986 | [M + H] + 373.3 | C17H24O9 | syringin | DS |
| 41 | 50.041 | [M – H] – 407.3 | C25H28O5 | 3-hydroxyglabrol | GC |
| 42 | 50.221 | [M – H] – (407.3) | C25H28O5 | glyinflanin A | GC |
a
DS: Radix codonopsis; BZ: Rhizoma atractylodis macrocephalae; FL: Poria; FF: Radix saposhnikoviae; BJT: Radix morindae officinalis; GC: Radix glycyrrhiza.