Figure 5.

New serum cytokine measurements. Serum levels of cytokines predicted to differ by the top models, plotted against the frequency with which subjects experienced viral URI that did not progress to otitis media. The sOP condition was associated with a significant positive effect on serum IL4 at low viral URI frequencies, while the interaction with viral URI frequency was associated with a significant decrease (*p < 0.05). Neither sOP condition nor viral URI frequency was significantly associated with changes in CXCL8.