The association between MEG3 and miR-143-3p. (A) The binding sites of MEG3 and miR-143-3p were predicted via starBase. (B) Luciferase activity was measured in PDLCs transfected with wt-MEG3 or mut-MEG3 and miR-143-3p mimic or miR-NC. (C) The level of miR-143-3p was measured in PDLCs transfected with OE-MEG3, vector, si-MEG3 or si-NC. (D, E) miR-143-3p level was examined in PDLCs transfected with OE-MEG3, vector, si-MEG3, or si-NC after treatment with LPS. * P<0.05.