TABLE 2.

Reviewed literature on OPC heterogeneity.

OPC heterogeneity	Differences in transcriptomics	Marques et al., 2016, 2018 Spitzer et al., 2019 Marisca et al., 2020
	Differential response to growth factors and cytokines	Mason and Goldman, 2002 Lin et al., 2009 Hill et al., 2013 Lentferink et al., 2018
	Region and age-dependent changes in physiological properties	Chittajallu et al., 2004 Karram et al., 2008 De Biase et al., 2010 Clarke et al., 2012 Moshrefi-Ravasdjani et al., 2017 Spitzer et al., 2019 Marisca et al., 2020
	Diverse proliferation and differentiation potential	Rivers et al., 2008 Vigano et al., 2013 Young et al., 2013 Marques et al., 2016 Moshrefi-Ravasdjani et al., 2017 Spitzer et al., 2019 Marisca et al., 2020

This table summarises the reviewed literature showing selected papers describing OPC heterogeneity. The references in blue suggest that OPCs are physiologically homogeneous.