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Comparison of the five LUT-TTR crystal structures. (A) Superimposition of 4QXV and 4DEV, the two crystal structures of wt-TTR in complex with LUT. (B) Comparison between wt-TTR-LUT (4QXY) versus V30M-TTR-LUT (4QYA). (C) Superposition of two LUT derivatives in complex with TTR.
