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. 2020 May 20;9(1):1011–1022. doi: 10.1080/22221751.2020.1763209

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© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Presence of CRISPR-Cas system in bla_KPC-positive /bla_KPC-negative groups and CG258/non-CG258 isolates. (A) i. Presence of type I-E CRISPR systems in 459 Chinese clinical isolates collected in this study; ii. Presence of type I-E CRISPR systems in 203 completely sequenced strains available in GenBank. (B) i. MLSTs of bla_KPC-positive group in459 Chinese clinical isolates; ii. MLSTs of bla_KPC-positive group in 203 completely sequenced strains available in GenBank. (C) i. Presence of type I-E CRISPR systems among different clone groups in 459 Chinese clinical isolates collected in this study; ii. Presence of type I-E systems among different clone groups in 203 completely sequenced strains available in GenBank. p < 0.0001 indicate significant differences between two groups as determined using Chi-square (and Fisher’s exact) test with Bonferroni correction of the GraphPad Prism8 software.