Table 3.
Comparison of genotype and allele distribution of DRD2/ANKK1 SNPs between schizophrenic patients with positive and negative family history of schizophrenia
| Family history of schizophrenia | n | Genotypes N (%) | χ2 | p | Alleles N (%) | χ2 | p | |||
|---|---|---|---|---|---|---|---|---|---|---|
| rs1799732 | ||||||||||
| C/C | C/del | del/del | 5.71 | 0.058 | C | del | 2.13 | 0.144 | ||
| Positive | 45 | 31 (69) | 14 (31) | 0 (0) | 76 (84) | 14 (16) | ||||
| Negative | 150 | 123 (82) | 24 (16) | 3 (2) | 270 (90) | 30 (10) | ||||
| rs6276 | ||||||||||
| A/A | A/G | G/G | 7.22 | 0.027 | A | G | 6.84 | 0.009 | ||
| Positive | 45 | 13 (29) | 22 (49) | 10 (22) | 48 (53) | 42 (47) | ||||
| Negative | 150 | 69 (46) | 67 (45) | 14 (9) | 205 (68) | 95 (32) | ||||
| rs1800497 | ||||||||||
| C/C | C/T | T/T | 0.94 | 0.625 | C | T | 0.94 | 0.333 | ||
| Positive | 45 | 32 (71) | 12 (27) | 1 (2) | 76 (84) | 14 (16) | ||||
| Negative | 149 | 95 (64) | 48 (32) | 6 (4) | 238 (80) | 60 (20) | ||||