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. Author manuscript; available in PMC: 2020 Jun 18.
Published in final edited form as: Curr Opin Physiol. 2018 Dec 1;8:23–29. doi: 10.1016/j.cophys.2018.11.008

Figure 4. Chondrolectin is a marker of size rather than type.

Figure 4.

A. Two examples of intracellular-labeled (neurobiotin, NB, green) motoneurons, coupled with ISH revelation of Chodl RNA (Chodl, red). In each experiment, a single MN was type-identified, labelled with an intracellular dye (NB), in order to recognize it among all the other MNs; and in situ hybridization against Chodl mARN was performed after fixation and slicing of the spinal cord. Left panel: Chodl− small FR motoneuron; Right panel: Chodl+ FF motoneuron. Scale bars: 15 μm. B. Contractile properties of the motor units tested for Chodl expression. The motoneurons indicated with arrows correspond to the two cells in D. Red circles are the motoneurons that expressed Chodl, while green squares are those that did not. The dashed lines at 8 mN and 20 ms separate the different types of MUs, and the dash-dotted line at 1.3 mN separates large from small MUs. C. Comparison of the average twitch amplitude of motor units split according to their expression of Chodl. D. Comparison of the proportion of cells expressing Chodl in the population of tested cells, split in two categories, large and small. Adapted from [22], licensed under CC-BY.