Table 2.
Hazard Ratio of The Association Between TC Quartiles at the time of GDM Diagnosis and Risk of Postpartum Impaired Glucose Tolerance (N = 845)
| N (%) | HR (95%CI) | P | Adjusted HR (95%CI)a | P | ||
|---|---|---|---|---|---|---|
| IGT | First | 83 (30.6) | Reference | Reference | ||
| Second | 64 (23.6) | 0.875 (0.631, 1.214) | 0.423 | 0.892 (0.642, 1.239) | 0.494 | |
| Third | 70 (25.9) | 0.704 (0.512, 0.968) | 0.031 | 0.703 (0.510, 0.971) | 0.032 | |
| Fourth | 54 (19.9) | 0.562 (0.395, 0.799) | 0.001 | 0.569 (0.400, 0.811) | 0.002 | |
| Prediabetesb | First | 84 (30.7) | Reference | Reference | ||
| Second | 64 (23.4) | 0.864 (0.623, 1.197) | 0.380 | 0.880 (0.634, 1.222) | 0.446 | |
| Third | 71 (25.9) | 0.705 (0.514, 0.968) | 0.031 | 0.705 (0.512, 0.971) | 0.032 | |
| Fourth | 55 (20.0) | 0.566 (0.400, 0.803) | 0.001 | 0.574 (0.404, 0.815) | 0.002 | |
| Type 2 diabetes | First | 15 (48.4) | Reference | Reference | ||
| Second | 6 (19.4) | 0.457 (0.177, 1.181) | 0.106 | 0.455 (0.176, 1.174) | 0.103 | |
| Third | 5 (16.1) | 0.242 (0.085, 0.687) | 0.008 | 0.239 (0.084, 0.680) | 0.007 | |
| Fourth | 5 (16.1) | 0.296 (0.106, 0.825) | 0.020 | 0.293 (0.105, 0.817) | 0.019 | |
| Postpartum glucose intolerancec | First | 99 (32.9) | Reference | Reference | ||
| Second | 70 (23.3) | 0.802 (0.590, 1.091) | 0.802 | 0.814 (0.598, 1.109) | 0.192 | |
| Third | 76 (25.2) | 0.634 (0.470, 0.856) | 0.003 | 0.632 (0.467, 0.855) | 0.003 | |
| Fourth | 56 (18.6) | 0.526 (0.379, 0.731) | 0.000 | 0.531 (0.382, 0.739) | 0.000 | |
TC total cholesterol, GDM gestational diabetes mellitus, HR hazard ratio, CI confidential interval, IGT impaired glucose tolerance
aadjusted for maternal age, pre-pregnancy BMI, time of diagnostic OGTT, time of postpartum OGTT, the concentrations of TG, HDL-c, LDL-c at time of GDM diagnosis and insulin treatment or not
bincluding both IFG and IGT
cincluding IFG, IGT and type 2 diabetes