Table 3.
Odds of Developing Incident Mobility Limitations in Men Aged 55 Years and Older
| Model 1* | Model 2** | |||
|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | |
| Associated w/ Baseline | Associated w/ Change§ | Associated w/ Baseline | Associated w/ Change§ | |
| Grip Strength, per 5 kg |
0.83 (0.71–0.96) |
1.00 | 0.81 | 0.92 |
| (0.84–1.20) | (0.69–0.95) | (0.76–1.13) | ||
| Grip Strength, per SD | 0.69 | 1.00 | 0.67 | 0.90 |
| (0.52–0.92) | (0.79–1.27) | (0.49–0.90) | (0.69–1.17) | |
| Grip Strength/BMI† | 0.50 | 1.05 | 0.47 | 0.86 |
| (0.37–0.68) | (0.83–1.33) | (0.34–0.66) | (0.65–1.13) | |
| ALMBMI† | 0.63 | 0.81 | 0.55 | 0.68 |
| (0.48–0.83) | (0.65–1.01) | (0.41–0.73) | (0.53–0.87) | |
| ALM/ht2† | 1.36 | 0.75 | 1.25 | 0.81 |
| (1.04–1.77) | (0.60–0.95) | (0.94–1.65) | (0.63–1.03) | |
| FNIH Cut Points | ||||
| Low ALMBMI, n = 5 (0.7%) | 4.37 (0.43–43.91) | |||
| Weakness, n = 8 (1.1%) | 2.83 (0.60–13.39) | |||
| Weakness/BMI, n = 19 (2.6%) | 4.01 (1.40–11.47) | |||
| Low ALMBMI plus Weakness, n = 0 | N/A | |||
| European Working Group Cut Points | ||||
| Low ALM/ht2 (EWGSOP2), n = 8 (1.1%) | 1.27 (0.12–13.27) | |||
| Weakness (EWGSOP2), n = 17 (2.3%) | 3.03 (1.0–9.18) | |||
| Low ALM and Weakness, n = 2 (0.3%) | 15.09 (0.71–320.09) |
Note: SD = Standard deviation; OR = Odds ratio; BMI = Body mass index; ALM = Appendicular lean mass; FNIH = Foundations for the National Institutes of Health; EWGSOP2 = European Working Group for Sarcopenia in Older People 2.
*Model 1 is adjusted for age, hypertension, diabetes and arthritis/gout;
**Model 2 is Model 1 but includes both baseline and change in the sarcopenia parameter;
§This column depicts the association between concurrent change in each sarcopenia characteristic, and incident mobility limitations after 6 years;
†Odds ratios and 95% confidence intervals are expressed per standard deviation (values in Supplementary Table S3, all column).