Table 3.
Sensitivity/Specificity of Various Definitions in Predicting Lack of Clinically Meaningful Improvement in Walking Speed at 6 mo (change in walking speed <0.10 m/s)
| BHS4 | BHS7 | ||||
|---|---|---|---|---|---|
| Definition | Cut point | Sensitivity (%) | Specificity (%) | Sensitivity (%) | Specificity (%) |
| Men | |||||
| SDOC Grip | <35.5 | — | — | 78 (29/37) | 53 (8/15) |
| SDOC Grip/BMI | <1.05 | — | — | 51 (19/37) | 80 (12/15) |
| SDOC Grip/TBF | <1.66 | — | — | 79 (27/34) | 67 (8/12) |
| SDOC Grip/arm lean mass | <6.08 | — | — | 82 (28/34) | 50 (6/12) |
| SDOC Grip/weight | <0.45 | — | — | 86 (32/37) | 60 (9/15) |
| FNIH Grip | <26.0 | — | — | 35 (13/37) | 80 (12/15) |
| FNIH Grip/BMI | <1.00 | — | — | 41 (15/37) | 80 (12/15) |
| EWGSOP* | — | — | — | 63 (22/35) | 46 (6/13) |
| Women | |||||
| SDOC Grip | <20.0 | 82 (68/83) | 36 (13/36) | 69 (37/54) | 35 (6/17) |
| SDOC Grip/BMI | <0.79 | 79 (63/80) | 47 (17/36) | 74 (40/54) | 53 (9/17) |
| SDOC Grip/TBF | <0.65 | 35 (25/72) | 74 (26/35) | 58 (25/43) | 93 (13/14) |
| SDOC Grip/arm lean mass | <3.26 | 22 (16/72) | 86 (30/35) | 21 (9/43) | 100 (14/14) |
| SDOC Grip/weight | <0.34 | 86 (71/83) | 25 (9/36) | 81 (44/54) | 41 (7/17) |
| FNIH Grip | <16.0 | 52 (43/83) | 67 (24/36) | 48 (26/54) | 71 (12/17) |
| FNIH Grip/BMI | <0.056 | 31 (25/80) | 81 (29/36) | 39 (21/54) | 88 (15/17) |
| EWGSOP* | — | 58 (41/71) | 51 (18/35) | 30 (13/43) | 14 (2/14) |
Note: BMI = body mass index; Grip = grip strength; TBF = total body fat.
*EWGSOP based on low lean mass (ALM/ht2 <7.23 and 5.67 kg/m2 in men and women, respectively) plus low strength (grip strength < 30 and <20 kg in men and women, respectively) and/or performance (walking speed < 0.8 m/s).