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[Preprint]. 2020 Jun 2:2020.05.28.20105692. [Version 1] doi: 10.1101/2020.05.28.20105692

Figure 2. Selection of antigens for neutralization PCR assay.

Figure 2.

Both full S1 and receptor binding domain (RBD) of S1 have the ability to engage with the ACE2. To evaluate suitability for neutralization PCR assay, we tested convalescent COVID19 patient sera (N=2, blue) and healthy donor sera (N=4, red) collected prior to the outbreak. Notably, the COVID19 sera were confirmed to harbor NAbs by pseudo-virus neutralization assay. The y-axis is the neutralization PCR assay signal ΔCt calculated by subtracting the Ct value of the sample from that of a buffer only blank control.